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1

Facile synthesis of 1-substituted 4,5-diaminopyrazoles and its application toward the synthesis of pyrazolo[3,4-b]pyrazines

Tun-Cheng Chien, Ronald A. Smaldone, Leroy B. Townsend

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 258 KB

english, 2004

2

Facile Synthesis of 1-Substituted 4,5-Diaminopyrazoles and Its Application Toward the Synthesis of Pyrazolo[3,4-b]pyrazines.

Tun-Cheng Chien, Ronald A. Smaldone, Leroy B. Townsend

Journal:

Year:

2004

File:

PDF, 124 KB

2004

3

GFP chromophore derivative suppresses ultraviolet A-induced JNK-signaling and apoptosis in keratinocytes, and adverse effects in zebrafish embryos

Wu, Nan-Lin, Lee, Te-An, Wang, Sheng-Fen, Li, Hsin-Ju, Chen, Hui-Ting, Chien, Tun-Cheng, Huang, Chieh-Chen, Hung, Chi-Feng

Journal:

Experimental Dermatology

Year:

2016

Language:

english

File:

PDF, 421 KB

english, 2016

4

Nucleosides. Part 11. Synthesis and Antiviral Evaluation of 5′-Alkylthio-5′-deoxy Quinazolinone Nucleoside Derivatives as S-Adenosyl-L-homocysteine Analogues.

Tun-Cheng Chien, Chien-Shu Chen, Fang-Hwa Yu, Ji-Wang Chern

Journal:

Year:

2005

File:

PDF, 30 KB

2005

5

ChemInform Abstract: Practical Synthesis of 6-Aryluridines via Palladium(II) Acetate Catalyzed Suzuki—Miyaura Cross-Coupling Reaction.

Yu-Chiao Shih, Tun-Cheng Chien

Journal:

Year:

2011

File:

PDF, 54 KB

2011

6

Mononuclear Heterocyclic Rearrangement: Synthesis of [5:5] Bicyclic [c]-Fused 3-Aminopyrazoles via the N—N Bond Formation Strategy.

David A. Berry, Tun-Cheng Chien, Leroy B. Townsend

Journal:

Year:

2005

File:

PDF, 26 KB

2005

7

Synthesis of 3-Aminoimidazo[4,5-c]pyrazole Nucleoside via the N-N Bond Formation Strategy as a [5:5] Fused Analog of Adenosine

Chien, Tun-Cheng, Berry, David A., Drach, John C., Townsend, Leroy B.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2005

Language:

english

File:

PDF, 580 KB

english, 2005

8

Reinvestigation of the Synthesis of 1-Deazauridine

Jen, Cheng-Hung, Chien, Tun-Cheng

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2010

Language:

english

File:

PDF, 647 KB

english, 2010

9

CuI-catalyzed Intramolecular Aminocyanation of Terminal Alkynes in N-(2-Ethynylphenyl)-N-sulfonylcyanamides via Cu-vinylidene Intermediates

Liao, Zhen-Yuan, Liao, Pen-Yuan, Chien, Tun-Cheng

Journal:

Chemical Communications

Year:

2016

Language:

english

File:

PDF, 683 KB

english, 2016

10

Reaction Mechanism of a Nonheme Iron Enzyme Catalyzed Oxidative Cyclization via C–C Bond Formation

Chang, Wei-chen, Yang, Zhi-Jie, Tu, Yueh-Hua, Chien, Tun-Cheng

Journal:

Organic Letters

Year:

2018

Language:

english

File:

PDF, 884 KB

english, 2018

11

ChemInform Abstract: Facile Synthesis of 4-Arylidene-5-imidazolinones as Synthetic Analogues of Fluorescent Protein Chromophore.

Lee, Cheng-Yu, Chen, Yun-Chung, Lin, Hao-Chun, Jhong, Yuandong, Chang, Chih-Wei, Tsai, Ching-Hua, Kao, Chai-Lin, Chien, Tun-Cheng

Journal:

Year:

2012

File:

PDF, 54 KB

2012

12

Biomimetic Approach toward the Total Synthesis of rac -2-(Acylmethylene)pyrrolidine Alkaloids

Shih, Yu-Chiao, Tsai, Pei-Hua, Hsu, Chia-Chun, Chang, Chih-Wei, Jhong, Yuandong, Chen, Yun-Chung, Chien, Tun-Cheng

Journal:

Journal of Organic Chemistry

Year:

2015

Language:

english

File:

PDF, 672 KB

english, 2015

13

Deciphering Pyrrolidine and Olefin Formation Mechanism in Kainic Acid Biosynthesis

Chen, Tzu-Yu, Xue, Shan, Tsai, Wei-Chih, Chien, Tun-Cheng, Guo, Yisong, Chang, Wei-chen

Journal:

Year:

2021

File:

PDF, 1.46 MB

2021

14

Practical synthesis of 6-aryluridines via palladium(II) acetate catalyzed Suzuki–Miyaura cross-coupling reaction

Yu-Chiao Shih, Tun-Cheng Chien

Journal:

Year:

2011

Language:

english

File:

PDF, 840 KB

english, 2011

15

Synthesis and Unexpected Oxidization of the Tricyclic Core of Ugibohlin, Isophakellin, and Styloguanidine

Chang, Chia-Wei, Wu, Chi-Cheng, Chang, Yung-Yu, Lin, Chia-Chi, Chien, Tun-Cheng

Journal:

Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 755 KB

english, 2013

16

Analysis of UDP- d -Apiose/UDP- d -Xylose Synthase-Catalyzed Conversion of UDP- d -Apiose Phosphonate to UDP- d -Xylose Phosphonate: Implications for a Retroaldol–Aldol Mechanism

Choi, Sei-hyun, Mansoorabadi, Steven O., Liu, Yung-nan, Chien, Tun-Cheng, Liu, Hung-wen

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 659 KB

english, 2012

17

A selective glucose sensor: cooperative effect by monoboronic acid-modified poly(amidoamine) dendrimers

Tsai, Ching-Hua, Tang, Yi-Hsuan, Chen, Hui-Ting, Yao, Yi-Wen, Chien, Tun-Cheng, Kao, Chai-Lin

Journal:

Chemical Communications

Year:

2018

Language:

english

File:

PDF, 656 KB

english, 2018

18

Regioselective arylation of uracil and 4-pyridone derivatives via copper(I) bromide mediated C–H bond activation

Cheng, Chien, Shih, Yu-Chiao, Chen, Hui-Ting, Chien, Tun-Cheng

Journal:

Year:

2013

Language:

english

File:

PDF, 564 KB

english, 2013

19

Mononuclear Heterocyclic Rearrangement: Synthesis of [5:5] Bicyclic [c]-Fused 3- Aminopyrazoles via the N-N Bond Formation Strategy

B. Townsend, Leroy, A. Berry, David, Chien, Tun-Cheng

Journal:

Year:

2004

Language:

english

File:

PDF, 132 KB

english, 2004

20

Nucleosides. Part 9. Synthesis of Purine N3,5′-Cyclonucleosides and N3,5′-Cyclo-2′,3′-seconucleosides via Mitsunobu Reaction as TIBO-Like Derivatives.

Grace Shiahuy Chen, Chien-Shu Chen, Tun-Cheng Chien, Jun-Yen Yeh, Chia-Chi Kuo, Rahul Subhash Talekar, Ji-Wang Chern

Journal:

Year:

2004

File:

PDF, 127 KB

2004

21

Synthesis and Antiviral Evaluation of Polyhalogenated Imidazole Nucleosides: Dimensional Analogues of 2,5,6-Trichloro-1-(β- d -ribofuranosyl)benzimidazole

Chien, Tun-Cheng, Saluja, Sunita S., Drach, John C., Townsend, Leroy B.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 184 KB

english, 2004

22

One-Pot Synthesis of N-Monosubstituted Ureas from Nitriles via Tiemann Rearrangement

Wang, Chien-Hong, Hsieh, Tsung-Han, Lin, Chia-Chi, Yeh, Wen-Hsiung, Lin, Chih-An, Chien, Tun-Cheng

Journal:

Year:

2015

Language:

english

File:

PDF, 172 KB

english, 2015

23

ChemInform Abstract: Regioselective Arylation of Uracil and 4-Pyridone Derivatives via Copper(I) Bromide Mediated C-H Bond Activation.

Cheng, Chien, Shih, Yu-Chiao, Chen, Hui-Ting, Chien, Tun-Cheng

Journal:

Year:

2013

File:

PDF, 27 KB

2013

24

Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry

Wang, Ying-Ren, Chen, Shin-Fu, Wu, Chyuan-Chuan, Liao, Yi-Wen, Lin, Te-Sheng, Liu, Ko-Ting, Chen, Yi-Song, Li, Tsai-Kun, Chien, Tun-Cheng, Chan, Nei-Li

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 5.09 MB

english, 2017

25

ChemInform Abstract: Practical Synthesis of N-Substituted Cyanamides via Tiemann Rearrangement of Amidoximes.

Lin, Chia-Chi, Hsieh, Tsung-Han, Liao, Pen-Yuan, Liao, Zhen-Yuan, Chang, Chih-Wei, Shih, Yu-Chiao, Yeh, Wen-Hsiung, Chien, Tun-Cheng

Journal:

Year:

2014

File:

PDF, 28 KB

2014

26

Facile synthesis of 4-arylidene-5-imidazolinones as synthetic analogs of fluorescent protein chromophore

Cheng-Yu Lee, Yun-Chung Chen, Hao-Chun Lin, Yuandong Jhong, Chih-Wei Chang, Ching-Hua Tsai, Chai-Lin Kao, Tun-Cheng Chien

Journal:

Year:

2012

Language:

english

File:

PDF, 506 KB

english, 2012

27

Synthesis of 6-Alkyluridines from 6-Cyanouridine via Zinc(II) Chloride-Catalyzed Nucleophilic Substitution with Alkyl Grignard Reagents

Shih, Yu-Chiao, Yang, Ya-Ying, Lin, Chun-Chi, Chien, Tun-Cheng

Journal:

Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 643 KB

english, 2013

28

Total Synthesis of Pseudouridine via Heck-type C-Glycosylation

Yu, Cheng-Ping, Chang, Hsin-Yun, Chien, Tun-Cheng

Journal:

New Journal of Chemistry

Year:

2019

Language:

english

File:

PDF, 1.14 MB

english, 2019

29

Nucleosides XI. Synthesis and Antiviral Evaluation of 5′-Alkylthio-5′-deoxy Quinazolinone Nucleoside Derivatives as S-Adenosyl-L-homocysteine Analogs

Chien, Tun-Cheng, Chen, Chien-Shu, Yu, Fang-Hwa, Chern, Ji-Wang

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2004

Language:

english

File:

PDF, 167 KB

english, 2004

30

Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry

Wang, Ying-Ren, Chen, Shin-Fu, Wu, Chyuan-Chuan, Liao, Yi-Wen, Lin, Te-Sheng, Liu, Ko-Ting, Chen, Yi-Song, Li, Tsai-Kun, Chien, Tun-Cheng, Chan, Nei-Li

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 415 KB

english, 2017

31

Facile Synthesis of 1-Substituted 2-Amino-3-cyanopyrroles: New Synthetic Precursors for 5,6-Unsubstituted Pyrrolo[2,3- d ]pyrimidines

Chien, Tun-Cheng, Meade, Eric A., Hinkley, Jack M., Townsend, Leroy B.

Journal:

Organic Letters

Year:

2004

Language:

english

File:

PDF, 54 KB

english, 2004

32

Chemical models and their mechanistic implications for the transformation of 6-cyanouridine 5′-monophosphate catalyzed by orotidine 5′-monophosphate decarboxylase

Wu, Yuen-Jen, Liao, Chen-Chieh, Jen, Cheng-Hung, Shih, Yu-Chiao, Chien, Tun-Cheng

Journal:

Chemical Communications

Year:

2010

Language:

english

File:

PDF, 544 KB

english, 2010

33

Nucleosides XII. 1 Synthesis of 5-Modified Isoguanosines and Reinvestigation of 5′-Deoxy- N 3 ,5′-cycloisoguanosine

Chien, Tun-Cheng, Kuo, Chia-Chi, Chen, Chien-Shu, Chern, Ji-Wang

Journal:

Journal of the Chinese Chemical Society

Year:

2004

Language:

english

File:

PDF, 74 KB

english, 2004

34

Practical Synthesis of N -Substituted Cyanamides via Tiemann Rearrangement of Amidoximes

Lin, Chia-Chi, Hsieh, Tsung-Han, Liao, Pen-Yuan, Liao, Zhen-Yuan, Chang, Chih-Wei, Shih, Yu-Chiao, Yeh, Wen-Hsiung, Chien, Tun-Cheng

Journal:

Organic Letters

Year:

2014

Language:

english

File:

PDF, 344 KB

english, 2014

35

Copper(I) Iodide-Catalyzed Synthesis of N,N′-Disubstituted Guanidines from N-Substituted Cyanamides

Zeng, Cian-Jhe, Chen, Chia-Jung, Chang, Chih-Wei, Chen, Hui-Ting, Chien, Tun-Cheng

Journal:

Australian Journal of Chemistry

Year:

2014

Language:

english

File:

PDF, 447 KB

english, 2014

36

Nucleosides XIII. Facile Synthesis of 4-Amino-1-(2-deoxy-β-D-ribofuranosyl)quinazolin-2-one as a 2′-Deoxycytidine Analog for Oligonucleotide Synthesis

Chien, Tun-Cheng, Chen, Chien-Shu, Chern, Ji-Wang

Journal:

Journal of the Chinese Chemical Society

Year:

2005

Language:

english

File:

PDF, 455 KB

english, 2005

37

Facile Synthesis of 1-Substituted 2-Amino-3-cyanopyrroles: New Synthetic Precursors for 5,6-Unsubstituted Pyrrolo[2,3-d]pyrimidines.

Tun-Cheng Chien, Eric A. Meade, Jack M. Hinkley, Leroy B. Townsend

Journal:

Year:

2004

File:

PDF, 27 KB

2004

38

Nucleosides VII:1 Synthesis of N-triphenylphosphoranylidene nucleosides by mitsunobu reaction. A novel protecting group for primary amines of nucleosides

Tun-Cheng Chien, Chien-Shu Chen, Jun-Yen Yeh, Kuang-Chao Wang, Wang Chern

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 236 KB

english, 1995

39

Identification of Reactive Intermediates for the Decarbonylative Reaction of 1-Alkylprolines

Shih, Yu-Chiao, Wang, Jing-Shiuan, Hsu, Chia-Chun, Tsai, Pei-Hua, Chien, Tun-Cheng

Journal:

Year:

2016

Language:

english

File:

PDF, 2.09 MB

english, 2016

40

Investigation of O -Sulfonylation-promoted Heterolytic NO Bond Cleavage of Amidoximes and Ketoximes

Hsieh, Tsung-Han, Liao, Pen-Yuan, Liu, Yu-Ting, Wang, Chien-Hong, Lin, Chia-Chi, Chien, Tun-Cheng

Journal:

Journal of the Chinese Chemical Society

Year:

2017

Language:

english

File:

PDF, 227 KB

english, 2017

41

A convenient preparation of 1,2,3-tri-O-acetyl-β-d-ribofuranose by enzymatic regioselective 5-O-deacetylation of the peracetylated ribofuranose

Tun-Cheng Chien, Ji-Wang Chern

Journal:

Carbohydrate Research

Year:

2004

Language:

english

File:

PDF, 240 KB

english, 2004

42

Study on the synthesis of 6-alkylaminouridines via the nucleophilic aromatic substitution reaction of 6-cyanouridine derivatives

Jian-Bang Lin, Jhih-Li He, Yu-Chiao Shih, Tun-Cheng Chien

Journal:

Tetrahedron Letters

Year:

2011

Language:

english

File:

PDF, 340 KB

english, 2011

43

ChemInform Abstract: Synthesis of 6-Alkyluridines from 6-Cyanouridine via Zinc(II) Chloride-Catalyzed Nucleophilic Substitution with Alkyl Grignard Reagents.

Shih, Yu-Chiao, Yang, Ya-Ying, Lin, Chun-Chi, Chien, Tun-Cheng

Journal:

Year:

2013

File:

PDF, 28 KB

2013

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